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CN750
CAS No. 2098711-72-7
CN750 ( CN-750;CN 750 )
产品货号. M13320 CAS No. 2098711-72-7
CN750 (CN-750) is novel BRD4 (BD1, 2) inhibitor with IC50 of 44 nM, MV4-11 IC50 of 0.54 uM.
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称CN750
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述CN750 (CN-750) is novel BRD4 (BD1, 2) inhibitor with IC50 of 44 nM, MV4-11 IC50 of 0.54 uM.
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产品描述CN750 (CN-750) is novel BRD4 (BD1, 2) inhibitor with IC50 of 44 nM, MV4-11 IC50 of 0.54 uM; shows Kd values of 33, 27, 24, 21, 20, 21, 18, 50, 20, 67, and 160 nM for BRD2 (BD1), BRD2 (BD1,2), BRD2 (BD2), BRD3 (BD1), BRD3 (BD1,2), BRD3 (BD2), BRD4 (BD1), BRD4 (BD2), BRDT (BD1), BRDT (BD1,2), and BRDT (BD2), respectively; CN750 is a pan BET family inhibitor.
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同义词CN-750;CN 750
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通路Chromatin/Epigenetic
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靶点Bromodomain
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受体Bromodomain
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研究领域——
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适应症——
化学信息
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CAS Number2098711-72-7
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分子量532.09
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分子式C29H34ClN7O
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纯度>98% (HPLC)
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溶解度——
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SMILESCN1C=C(C=CC1=O)C2=CC3=C(C=C2)N=C(N=C3NCC4=CC(=CC=C4)Cl)N5CCN(CC5)CCN(C)C
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化学全称5-(4-((3-chlorobenzyl)amino)-2-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)quinazolin-6-yl)-1-methylpyridin-2(1H)-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Yang SM, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3483-3488.
产品手册
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