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CI-976
CAS No. 114289-47-3
CI-976 ( PD 128042 )
产品货号. M10507 CAS No. 114289-47-3
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥494 | 有现货 |
|
| 5MG | ￥705 | 有现货 |
|
| 10MG | ￥1045 | 有现货 |
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| 25MG | ￥2260 | 有现货 |
|
| 50MG | ￥4204 | 有现货 |
|
| 100MG | ￥6091 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CI-976
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
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产品描述CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM; decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits.Atherosclerosis Discontinued
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同义词PD 128042
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Cardiovascular Disease
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适应症Atherosclerosis
化学信息
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CAS Number114289-47-3
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分子量393.57
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分子式C23H39NO4
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纯度>98% (HPLC)
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溶解度——
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SMILESCCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC
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化学全称2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Field FJ, et al. Lipids. 1991 Jan;26(1):1-8.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10;37(12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb;34(2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr;376(1-2):151-61.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10;37(12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb;34(2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr;376(1-2):151-61.
