CDDO-3P-Im

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

CDDO-3P-Im, an analog of CDDO-Imidazolide, has a chemopreventive effect. It can reduce the size and severity of the lung tumors in the mouse lung cancer model.

CDDO-3P-Im, an analog of CDDO-Imidazolide, has a chemopreventive effect. It can reduce the size and severity of the lung tumors in the mouse lung cancer model.(In Vitro):CDDO-3P-Im (30 nM) induces differentiation of U937 cells. In RAW264.7 cells, CDDO-3P-Im suppresses NO production (IC50 = 4.3 nM).(In Vivo):CDDO-3P-Im reduces the size and the severity of the lung tumors in mouse lung cancer models. In A/J mice, CDDO-3P-Im (50-200 mg/kg; diet) decreases the number, size, and severity of tumors. CDDO-3P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels in various mouse tissues.

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Others

Other Targets

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1883650-95-0

618.8

C39H46N4O3

>98% (HPLC)

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[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]3(C)C=C(C#N)C(=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)n1cnc(c1)-c1cccnc1

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(-20℃)

With Ice Pack

≥ 2 years