CDDO-2P-Im
CAS No. 1883650-96-1
CDDO-2P-Im ( CDDO-2-P-Im )
产品货号. M26555 CAS No. 1883650-96-1
CDDO-2P-Im, an analog of CDDO-Imidazolide, has a chemopreventive effect. It can reduce the size and severity of the lung tumors in the mouse lung cancer model.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1847 | 有现货 |
|
10MG | ¥3013 | 有现货 |
|
25MG | ¥4982 | 有现货 |
|
50MG | ¥7039 | 有现货 |
|
100MG | ¥9477 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称CDDO-2P-Im
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述CDDO-2P-Im, an analog of CDDO-Imidazolide, has a chemopreventive effect. It can reduce the size and severity of the lung tumors in the mouse lung cancer model.
-
产品描述CDDO-2P-Im, an analog of CDDO-Imidazolide, has a chemopreventive effect. It can reduce the size and severity of the lung tumors in the mouse lung cancer model.(In Vitro):In RAW264.7 cells, CDDO-2P-Im suppresses NO production (IC50: 5.8 nM). CDDO-2P-Im (100 nM) induces differentiation of U937 cells.(In Vivo):CDDO-2P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels. In A/J mice, CDDO-2P-Im (50-200 mg/kg) decreases the number, size, and severity of tumors.
-
同义词CDDO-2-P-Im
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number1883650-96-1
-
分子量618.8
-
分子式C39H46N4O3
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]3(C)C=C(C#N)C(=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)n1cnc(c1)-c1ccccn1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Zhang J, et al. Low dose of Bisphenol A enhance the susceptibility of thyroid carcinoma stimulated by DHPN and iodine excess in F344 rats. Oncotarget. 2017 Jul 22;8(41):69874-69887.
产品手册
关联产品
-
3,4,5-Tricaffeoylqui...
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor 4 expression-mediated activation of the Akt, ERK and NF-κB pathways, it may exert an inhibitory effect against the pro-inflammatory mediator-induced skin disease.
-
ASCORBYL GLUCOSIDE
ASCORBYL GLUCOSIDE is a glucoside derivative of ascorbic acid shows anti-cancer activity after enzymatic hydrolysis to ascorbic acid.
-
Trioxsalen
Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema.