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首页- Products - Others - Other Targets - CCI-006

CCI-006

CAS No. 292053-42-0

CCI-006 ( —— )

产品货号. M22449 CAS No. 292053-42-0

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ￥1158 有现货
5MG ￥2001 有现货
10MG ￥3143 有现货
25MG ￥5249 有现货
50MG ￥7501 有现货
100MG ￥10206 有现货
500MG ￥20412 有现货
1G 获取报价 有现货
拼团 产品询价 大包装询价 加入购物车

生物学信息

  • 产品名称
    CCI-006
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
  • 产品描述
    CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Mitochondria
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    292053-42-0
  • 分子量
    332.33
  • 分子式
    C15H12N2O5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:83.33 mg/mL (250.74 mM)
  • SMILES
    COC(=O)C(\C#N)=C\c1ccc(o1)-c1ccc(cc1)S(N)(=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.
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