CCI-006
CAS No. 292053-42-0
CCI-006 ( —— )
产品货号. M22449 CAS No. 292053-42-0
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1158 | 有现货 |
|
5MG | ¥2001 | 有现货 |
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10MG | ¥3143 | 有现货 |
|
25MG | ¥5249 | 有现货 |
|
50MG | ¥7501 | 有现货 |
|
100MG | ¥10206 | 有现货 |
|
500MG | ¥20412 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CCI-006
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
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产品描述CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
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同义词——
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通路Others
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靶点Other Targets
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受体Mitochondria
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研究领域——
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适应症——
化学信息
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CAS Number292053-42-0
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分子量332.33
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分子式C15H12N2O5S
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纯度>98% (HPLC)
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溶解度DMSO:83.33 mg/mL (250.74 mM)
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SMILESCOC(=O)C(\C#N)=C\c1ccc(o1)-c1ccc(cc1)S(N)(=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.
产品手册
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