• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

CCI-006

CAS No. 292053-42-0

CCI-006 ( —— )

产品货号. M22449 CAS No. 292053-42-0

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥1158 有现货
5MG ¥2001 有现货
10MG ¥3143 有现货
25MG ¥5249 有现货
50MG ¥7501 有现货
100MG ¥10206 有现货
500MG ¥20412 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CCI-006
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
  • 产品描述
    CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Mitochondria
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    292053-42-0
  • 分子量
    332.33
  • 分子式
    C15H12N2O5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:83.33 mg/mL (250.74 mM)
  • SMILES
    COC(=O)C(\C#N)=C\c1ccc(o1)-c1ccc(cc1)S(N)(=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.
产品手册
关联产品
  • Cytidine 5'-diphosph...

    Cytidine 5'-diphosphate trisodium salt can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK).

  • Super-TDU (1-31) TFA

    Super-tdu (1-31) TFA is an endogenous ligand of heptapeptide receptor and has a strong anti-analgesic effect.

  • Safflower yellow

    Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius).