CCCP ( CCCP; Mesoxalonitrile 3-chlorophenylhydrazone )

产品货号. M18806 CAS No. 555-60-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

CCCP
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP).
产品描述

m-Cl-CCP [555-60-2] is a protonophore (h+ ionophore) and uncoupler of oxidative phosphorylation in mitochondria, inhibiting secretion of hepatic lipase and partially inhibiting the ph gradient-activated cl- uptake and cl-/cl- exchange activities in brush-border membrane vesicles
同义词

CCCP; Mesoxalonitrile 3-chlorophenylhydrazone
通路

Others
靶点

Other Targets
受体

TBK1; IFN-β
研究领域

——
适应症

——

1. Kwon D, et al. Biochem Biophys Res Commun. 2017 Aug 30. pii: S0006-291X(17)31704-7.

计算器

产品手册

关联产品

Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
Angelol G

Angelol G is a natural product from Angelica sinensis.
3′-Deoxythymidine

3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor.