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CAY10444
CAS No. 298186-80-8
CAY10444 ( —— )
产品货号. M33970 CAS No. 298186-80-8
CAY10444 (BML-241) 是一种 sphingosine-1-phosphate 3 (S1P3) 拮抗剂。CAY10444 在表达 S1P3 受体的 HeLa 细胞中抑制 37% S1P 诱导的 Ca2+ 增加。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥315 | 有现货 |
|
| 10MG | ￥549 | 有现货 |
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| 25MG | ￥1150 | 有现货 |
|
| 50MG | ￥1932 | 有现货 |
|
| 100MG | ￥3159 | 有现货 |
|
| 200MG | ￥4292 | 有现货 |
|
| 500MG | ￥6755 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CAY10444
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CAY10444 (BML-241) 是一种 sphingosine-1-phosphate 3 (S1P3) 拮抗剂。CAY10444 在表达 S1P3 受体的 HeLa 细胞中抑制 37% S1P 诱导的 Ca2+ 增加。
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产品描述CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors.
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体外实验BML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number298186-80-8
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分子量287.46
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分子式C15H29NO2S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 41.67 mg/mL (144.96 mM; 超声助溶 (<80°C)
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SMILESCCCCCCCCCCCC1N[C@@H](CS1)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Salvatore Salomone, et al. Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol. 2011 Feb 22;2:9. ?
产品手册
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