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Bococizumab
CAS No. 1407495-02-6
Bococizumab ( —— )
产品货号. M36692 CAS No. 1407495-02-6
Bococizumab (PF-04950615) 是一种抗-人 PCSK9 的抗体抑制剂，可降低低密度脂蛋白胆固醇 (LDL-C) 水平。Bococizumab 可用于高胆固醇血症的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥4483 | 有现货 |
|
| 5MG | ￥7041 | 有现货 |
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| 10MG | ￥11224 | 有现货 |
|
| 25MG | ￥15484 | 有现货 |
|
| 50MG | ￥21740 | 有现货 |
|
| 100MG | ￥28688 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Bococizumab
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Bococizumab (PF-04950615) 是一种抗-人 PCSK9 的抗体抑制剂，可降低低密度脂蛋白胆固醇 (LDL-C) 水平。Bococizumab 可用于高胆固醇血症的研究。
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产品描述Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia.
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体外实验——
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体内实验Bococizumab (0-100 mg/kg, i.v.) decreases maternal and fetal cholesterol and does not affect rat embryo-fetal development.Animal Model:Pregnant Sprague-Dawley (SD) rats Dosage:0, 10, 30, and 100 mg/kg Administration:Intravenous injection (i.v.)Result:Decreased in fetal cholesterol levels.Showed well tolerance and no effects on ovarian or uterine parameters.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1407495-02-6
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Koutaro Yokote, et al. Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive - Results From a Randomized, Placebo-Controlled, Dose-Ranging Study. Circ J. 2017 Sep 25;81(10):1496-1505. ?
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