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Boc-C16-COOH
CAS No. 843666-40-0
Boc-C16-COOH ( —— )
产品货号. M28901 CAS No. 843666-40-0
Boc-C16-COOH 是一种基于烷基链的 PROTAC 连接体。 Boc-C16-COOH 是一种不可切割的 ADC 连接子,用于合成抗体药物偶联物 (ADC)。
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
1G | ¥324 | 有现货 |
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生物学信息
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产品名称Boc-C16-COOH
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Boc-C16-COOH 是一种基于烷基链的 PROTAC 连接体。 Boc-C16-COOH 是一种不可切割的 ADC 连接子,用于合成抗体药物偶联物 (ADC)。
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产品描述Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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体外实验ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体CRF|inflammation
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研究领域——
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适应症——
化学信息
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CAS Number843666-40-0
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分子量370.574
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分子式C22H42O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (269.85 mM)
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SMILESCC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Zorrilla EP, et al. Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat. Brain Res. 2002 Oct 18;952(2):188-99.
产品手册
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