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Bis-Tos-PEG4
CAS No. 37860-51-8
Bis-Tos-PEG4 ( PROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate) )
产品货号. M27007 CAS No. 37860-51-8
Bis-Tos-PEG4 (PROTAC Linker 16) 是一种基于 PEG 的 PROTAC 连接子，可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥332 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Bis-Tos-PEG4
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Bis-Tos-PEG4 (PROTAC Linker 16) 是一种基于 PEG 的 PROTAC 连接子，可用于 PROTAC 的合成。
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产品描述Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词PROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate)
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通路Others
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靶点Other Targets
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受体Bcl-2| Caspase-3
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研究领域——
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适应症——
化学信息
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CAS Number37860-51-8
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分子量502.59
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分子式C22H30O9S2
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Golla Madhubabu, et al. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Toxicol In Vitro. 2014 Dec;28(8):1386-95.
产品手册
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