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Bis-Tos-PEG4

CAS No. 37860-51-8

Bis-Tos-PEG4 ( PROTAC Linker 16; 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane; Tetraethylene glycol di(p-toluenesulfonate) )

产品货号. M27007 CAS No. 37860-51-8

Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥332 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Bis-Tos-PEG4
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
  • 产品描述
    Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • 同义词
    PROTAC Linker 16; 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane; Tetraethylene glycol di(p-toluenesulfonate)
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Bcl-2; Caspase-3
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    37860-51-8
  • 分子量
    502.6
  • 分子式
    C22H30O9S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Golla Madhubabu, et al. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Toxicol In Vitro. 2014 Dec;28(8):1386-95.
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