Bis-Tos-PEG4
CAS No. 37860-51-8
Bis-Tos-PEG4 ( PROTAC Linker 16; 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane; Tetraethylene glycol di(p-toluenesulfonate) )
产品货号. M27007 CAS No. 37860-51-8
Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥332 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Bis-Tos-PEG4
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
-
产品描述Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
同义词PROTAC Linker 16; 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane; Tetraethylene glycol di(p-toluenesulfonate)
-
通路Others
-
靶点Other Targets
-
受体Bcl-2; Caspase-3
-
研究领域——
-
适应症——
化学信息
-
CAS Number37860-51-8
-
分子量502.6
-
分子式C22H30O9S2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Golla Madhubabu, et al. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Toxicol In Vitro. 2014 Dec;28(8):1386-95.
产品手册
关联产品
-
ADWX 1
Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. Ameliorates rat experimental autoimmune encephalomyelitis, in a model for multiple sclerosis.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
MSC2504877
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.