Biotin-PEG6-Boc ( Biotin-PEG6-t-butyl ester )

产品货号. M26910 CAS No. 1352814-07-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Biotin-PEG6-Boc
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Biotin-PEG6-Boc 是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。
产品描述

Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体内实验

——
同义词

Biotin-PEG6-t-butyl ester
通路

Others
靶点

Other Targets
受体

GPR40
研究领域

——
适应症

——

CAS Number

1352814-07-3
分子量

635.81
分子式

C29H53N3O10S
纯度

>98% (HPLC)
溶解度

——
SMILES

[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C)[C@@]1([H])NC(=O)N2
化学全称

——

1.Houze JB, et al. AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1267-70.

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