Bimolane ( AT-1727 | AT1727 | CCRIS 7574 | Bimolane )

产品货号. M19065 CAS No. 74550-97-3

Bimolane 是一种拓扑异构酶 II 抑制剂。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥284	有现货
5MG	￥421	有现货
10MG	￥705	有现货
25MG	￥1685	有现货
50MG	￥2916	有现货
100MG	￥3985	有现货
500MG	￥9072	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Bimolane
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Bimolane 是一种拓扑异构酶 II 抑制剂。
产品描述

Bimolane is a topoisomerase II inhibitor. Bimolane has been widely used in China as an anti-neoplastic agent and for the treatment of psoriasis. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors. These results provide evidence that bimolane is an inhibitor of topoisomerase II in vitro.
体外实验

——
体内实验

——
同义词

AT-1727 | AT1727 | CCRIS 7574 | Bimolane
通路

Others
靶点

Other Targets
受体

Topo II
研究领域

——
适应症

——

化学信息

CAS Number

74550-97-3
分子量

452.51
分子式

C20H32N6O6
纯度

>98% (HPLC)
溶解度

——
SMILES

N1(C(=O)CN(CC1=O)CCN1CC(=O)N(C(=O)C1)CN1CCOCC1)CN1CCOCC1
化学全称

1-(morpholin-4-ylmethyl)-4-[2-[4-(morpholin-4-ylmethyl)-3,5-dioxopiperazin-1-yl]ethyl]piperazine-2,6-dione

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Vuong MC, Hasegawa LS, Eastmond DA. A comparative study of the cytotoxic and genotoxic effects of ICRF-154 and bimolane, two catalytic inhibitors of topoisomerase II. Mutat Res. 2013 Jan 20;750(1-2):63-71.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册