021-51111890
购物车（）
sales@molnova.cn
Bimolane
CAS No. 74550-97-3
Bimolane ( AT-1727; AT1727; CCRIS 7574;Bimolane )
产品货号. M19065 CAS No. 74550-97-3
Bimolane is a topoisomerase II inhibitor.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥284 | 有现货 |
|
| 5MG | ￥421 | 有现货 |
|
| 10MG | ￥705 | 有现货 |
|
| 25MG | ￥1685 | 有现货 |
|
| 50MG | ￥2916 | 有现货 |
|
| 100MG | ￥3985 | 有现货 |
|
| 500MG | ￥9072 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Bimolane
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Bimolane is a topoisomerase II inhibitor.
-
产品描述Bimolane is a topoisomerase II inhibitor. Bimolane has been widely used in China as an anti-neoplastic agent and for the treatment of psoriasis. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors. These results provide evidence that bimolane is an inhibitor of topoisomerase II in vitro.
-
同义词AT-1727; AT1727; CCRIS 7574;Bimolane
-
通路Others
-
靶点Other Targets
-
受体Topo II
-
研究领域——
-
适应症——
化学信息
-
CAS Number74550-97-3
-
分子量452.51
-
分子式C20H32N6O6
-
纯度98%
-
溶解度——
-
SMILESN1(C(=O)CN(CC1=O)CCN1CC(=O)N(C(=O)C1)CN1CCOCC1)CN1CCOCC1
-
化学全称1-(morpholin-4-ylmethyl)-4-[2-[4-(morpholin-4-ylmethyl)-3,5-dioxopiperazin-1-yl]ethyl]piperazine-2,6-dione
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Vuong MC, Hasegawa LS, Eastmond DA. A comparative study of the cytotoxic and genotoxic effects of ICRF-154 and bimolane, two catalytic inhibitors of topoisomerase II. Mutat Res. 2013 Jan 20;750(1-2):63-71.
产品手册
关联产品
-
Dihydroethidium
Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator.
-
7-Methylcoumarin
7-Methylcoumarin with strong hepatoprotective activity.
-
Trametenolic acid
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.
