Balsalazide ( Balsalazide )

产品货号. M19126 CAS No. 80573-04-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Balsalazide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Balsalazide 是一种抗炎化合物，用于治疗炎症性肠病。
产品描述

Balsalazide is an anti-inflammatory agent for treatment of Inflammatory Bowel Disease.
体外实验

——
体内实验

At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug.
同义词

Balsalazide
通路

Others
靶点

Other Targets
受体

Lipoxygenase
研究领域

Inflammation/Immunology
适应症

——

CAS Number

80573-04-2
分子量

357.32
分子式

C17H15N3O6
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 41 mg/mL; 114.74 mM
SMILES

OC(=O)CCNC(=O)c1ccc(cc1)\N=N\c1ccc(O)c(c1)C(O)=O
化学全称

(E)-5-[[[-4-(2-Carboxyethyl)aminocarbonyl]phenyl]azo]-2-hydroxybenzoic acid

1. Kruis W, et al. Gut, 2001. 49(6): p. 783-789.

计算器

产品手册

关联产品

3,5-Di-O-caffeoylqui...

3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells. 3,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV.
Tecovirimat

Tecovirimat (ST-246, Tpoxx) 是一种有效的、口服生物可利用的、一流的正痘病毒出口抑制剂，针对一组正痘病毒的 EC50 为 0.01-0.6 uM。
Transdermal Peptide ...

Transdermal Peptide TFA (TD 1 Peptide TFA) is an 11-amino acid polypeptide that binds to Na+/K+ -atpase beta-subunit (ATP1B1) and interacts with the C terminal of ATP1B1.Transdermal Peptide TFA can enhance the transmission of some large molecules in the skin.