Balsalazide ( Balsalazide )

产品货号. M19126 CAS No. 80573-04-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Balsalazide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Balsalazide 是一种抗炎化合物，用于治疗炎症性肠病。
产品描述

Balsalazide is an anti-inflammatory agent for treatment of Inflammatory Bowel Disease.
体外实验

——
体内实验

At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug.
同义词

Balsalazide
通路

Others
靶点

Other Targets
受体

Lipoxygenase
研究领域

Inflammation/Immunology
适应症

——

CAS Number

80573-04-2
分子量

357.32
分子式

C17H15N3O6
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 41 mg/mL; 114.74 mM
SMILES

OC(=O)CCNC(=O)c1ccc(cc1)\N=N\c1ccc(O)c(c1)C(O)=O
化学全称

(E)-5-[[[-4-(2-Carboxyethyl)aminocarbonyl]phenyl]azo]-2-hydroxybenzoic acid