Bacitracin ( Bacitracin )

产品货号. M11703 CAS No. 1405-87-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Bacitracin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy.
产品描述

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.
同义词

Bacitracin
通路

Others
靶点

Other Targets
受体

Others
研究领域

Other Indications
适应症

——

CAS Number

1405-87-4
分子量

1422.73
分子式

C66H103N17O16S
纯度

>98%(HPLC)
溶解度

Water: 100 mg/mL (70.98 mM); DMSO: 100 mg/mL (70.98 mM)
SMILES

O=C(O)CC[C@@H](NC([C@@H](NC([C@H]1N=C([C@@H](N)[C@@H](C)CC)SC1)=O)CC(C)C)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]2C(N[C@H](CCCN)C(N[C@@H]([C@H](CC)C)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CN=CN4)C(N[C@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(NCCCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O
化学全称

(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

1.Toscano WA Jr, et al. Pharmacol Ther, 1982, 16(2), 199-210.

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