BTT-369 ( BTT 369 | BTT 369 )

产品货号. M17024 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BTT-369
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BTT-369 (BTT369) 是一种电压门控 CaV2.2 钙通道抑制剂。
产品描述

BTT-369 (BTT369) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction with Ki of 2.0 uM in FP assays; decreases trafficking of CaV2.2 channels to the plasma membrane and modulates the functions of the channel, suppresses pain responses in rodent neuropathic pain models; BTT-369 (BTT369) is a cell-permeable derivative of BTT-266.
体外实验

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体内实验

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同义词

BTT 369 | BTT 369
通路

GPCR/G Protein
靶点

Calcium Channel
受体

Calcium Channel
研究领域

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适应症

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CAS Number

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分子量

580.652
分子式

C34H28N8O2
纯度

>98% (HPLC)
溶解度

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SMILES

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化学全称

(3-(1H-tetrazol-5-yl)phenyl)(5-(4-methoxyphenyl)-1'-phenyl-3'-(p-tolyl)-3,4-dihydro-1'H,2H-[3,4'-bipyrazol]-2-yl)methanone