BTS

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

高度特异性的肌球蛋白 II ATP 酶抑制剂；抑制 Ca2+ 刺激的 S1 ATP 酶，并可逆地阻止滑行运动。

A highly specific myosin II ATPase inhibitor; inhibits the Ca2+-stimulated S1 ATPase, and reversibly blocked gliding motility; inhibits isometric Ca2+-activated tension with IC50 of 3 uM in glycerol-extracted fibres from rabbit psoas muscle; specific and no activity for platelet myosin II.

BTS (2-12 μM) inhibits the Ca2+-stimulated ATPase activity of myosin S1 in the absence of actin, with an IC50 of ~5 μM.BTS (2-20 μM) reversibly inhibits the gliding motility rate of heavy meromyosin (HMM).BTS (100 μM) releases myosin from actin in the presence of ADP.BTS (0-20 μM) reversibly inhibits isometric Ca2+-activated tension in skinned skeletal muscle fibres from rabbit and frog, with IC50s of ~3 μM and 1 μM, respectively.

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N-Benzyl-p-toluenesulfonamide | N-Tosylbenzylamine

Cytoskeleton/Cell Adhesion Molecules

Myosin

Myosin

Cancer

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1576-37-0

261.3394

C14H15NO2S

>98% (HPLC)

10 mM in DMSO

O=S(C1=CC=C(C)C=C1)(NCC2=CC=CC=C2)=O

Benzenesulfonamide, 4-methyl-N-(phenylmethyl)-

(-20℃)

With Ice Pack

≥ 2 years