BPTU ( BPTU; BMS-646786; BMS 646786 )

产品货号. M17632 CAS No. 870544-59-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BPTU
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle.
产品描述

Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic; reduces platelet aggregation.
同义词

BPTU; BMS-646786; BMS 646786
通路

Others
靶点

Other Targets
受体

P2Y1
研究领域

Cardiovascular Disease
适应症

——

CAS Number

870544-59-5
分子量

445.42
分子式

C23H22F3N3O3
纯度

98%
溶解度

DMSO : ≥ 33.3 mg/mL. 74.76 mM; H2O : < 0.1 mg/mL
SMILES

CC(C)(C)C1=CC=CC=C1OC2=C(C=CC=N2)NC(=O)NC3=CC=C(C=C3)OC(F)(F)F
化学全称

1-[2-(2-tert-Butylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]urea

1.Abrahamsen B, et al. J Neurosci. 2013 Jan 16;33(3):1068-87.

计算器

产品手册

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