BPH-1358 ( NSC50460 )

产品货号. M24517 CAS No. 5352-53-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BPH-1358
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor.
产品描述

BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL).
同义词

NSC50460
通路

Others
靶点

Other Targets
受体

human bisphosphonate farnesyl diphosphate synthase
研究领域

——
适应症

——

CAS Number

5352-53-4
分子量

601.5
分子式

C32H30Cl2N6O2
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5.[H]Cl.[H]Cl
化学全称

——

1.Zhu W, et al. Antibacterial drug leads: DNA and enzyme multitargeting. J Med Chem. 2015 Feb 12;58(3):1215-27.

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