021-51111890
购物车（）
sales@molnova.cn
BMS-394136
CAS No. 343246-73-1
BMS-394136 ( BMS394136 )
产品货号. M14168 CAS No. 343246-73-1
BMS-394136 is a potent, selective IKur/Kv1.5inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥5233 | 有现货 |
|
| 10MG | ￥7444 | 有现货 |
|
| 25MG | ￥11178 | 有现货 |
|
| 50MG | ￥15066 | 有现货 |
|
| 100MG | ￥20169 | 有现货 |
|
| 500MG | ￥39933 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称BMS-394136
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述BMS-394136 is a potent, selective IKur/Kv1.5inhibitor.
-
产品描述BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.Heart Arrhythmia Phase 1 Discontinued
-
同义词BMS394136
-
通路Cell Cycle/DNA Damage
-
靶点Potassium Channel
-
受体Potassium Channel
-
研究领域Cardiovascular Disease
-
适应症Heart Arrhythmia
化学信息
-
CAS Number343246-73-1
-
分子量471.36
-
分子式C24H21Cl2FN4O
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCC1=C([C@H](n2c(ccn2)N1)c3ccc(c(c3)Cl)Cl)C(=O)N4CCC[C@H]4c5ccc(cc5)F
-
化学全称Pyrrolidine, 1-[[(7R)-7-(3,4-dichlorophenyl)-4,7-dihydro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]carbonyl]-2-(4-fluorophenyl)-, (2S)- (9CI)
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Dezhi Xing, et al. Abstract 2515: A Selective IKur Blocker, BMS-394136 Selectively Prolongs Atrial APD and Refractoriness in Beagles and Rabbits. Circulation. 2009;120:S654.
产品手册
关联产品
-
Dronedarone hydrochl...
A multichannel blocker agent that has antiarrhythmic activity.
-
BMS-191011
BMS-191011 is an activator of large-conductance calcium-activated potassium (BKCa) channels effective in stroke models.
-
Flupirtine
A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.
