021-51111890
购物车（）
sales@molnova.cn
BL-1020
CAS No. 503537-33-5
BL-1020 ( BL1020;BL 1020 )
产品货号. M14710 CAS No. 503537-33-5
BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称BL-1020
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist.
-
产品描述BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist; reduces dopamine activity and enhances GABAA activity, shows pro-cognitive effects and potential for the treatment of schizophrenia; displays strong dopamine and serotonin (5HT) receptor inhibition ((D2LK(iz)=0.066 nM, D(2S)Ki=0.062 nM, 5-HT2A Ki=0.21 nM).Schizophrenia Phase 2 Discontinued
-
同义词BL1020;BL 1020
-
通路GPCR/G Protein
-
靶点Dopamine Receptor
-
受体Dopamine Receptor
-
研究领域Neurological Disease
-
适应症Schizophrenia
化学信息
-
CAS Number503537-33-5
-
分子量525.53
-
分子式C25H34Cl2N4O2S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl 4-aminobutanoate hydrochloride
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Geffen Y, et al. Eur Neuropsychopharmacol. 2009 Jan;19(1):1-13.
2. Nudelman A, et al. J Med Chem. 2008 May 8;51(9):2858-62.
3. Appel L, et al. Eur Neuropsychopharmacol. 2009 Dec;19(12):841-50.
4. Geffen Y, et al. J Clin Psychiatry. 2012 Sep;73(9):e1168-74.
2. Nudelman A, et al. J Med Chem. 2008 May 8;51(9):2858-62.
3. Appel L, et al. Eur Neuropsychopharmacol. 2009 Dec;19(12):841-50.
4. Geffen Y, et al. J Clin Psychiatry. 2012 Sep;73(9):e1168-74.
产品手册
关联产品
-
Octodrine hydrochlor...
Octodrine hydrochloride is a central nervous stimulant that increases the uptake of dopamine and noradrenaline.
-
Cabergoline
Cabergoline is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.Cabergoline acts as a potent agonist of D2, D3 and 5-HT2B receptors.
-
Trimethobenzamide hy...
Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
