BAW2881
CAS No. 861875-60-7
BAW2881 ( BAW2881; BAW-2881; BAW 2881 )
产品货号. M17624 CAS No. 861875-60-7
BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥348 | 有现货 |
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5MG | ¥551 | 有现货 |
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10MG | ¥948 | 有现货 |
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25MG | ¥1806 | 有现货 |
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50MG | ¥2916 | 有现货 |
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100MG | ¥4228 | 有现货 |
|
500MG | ¥9477 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BAW2881
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.
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产品描述BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation. NVP-BAW2881 inhibited proliferation, migration, and tube formation by human umbilical vein endothelial cells and lymphatic endothelial cells in vitro. NVP-BAW2881 reduced the number of blood and lymphatic vessels and infiltrating leukocytes in the skin, and normalized the epidermal architecture. NVP-BAW2881 also displayed strong anti-inflammatory effects in models of acute inflammation; pretreatment with topical NVP-BAW2881 significantly inhibited VEGF-A-induced vascular permeability in the skin of pigs and mice.
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同义词BAW2881; BAW-2881; BAW 2881
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通路Others
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靶点Other Targets
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受体c-Abl; B-Raf (V599E); C-Raf-1; hVEGFR2
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研究领域Endocrinology
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适应症——
化学信息
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CAS Number861875-60-7
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分子量424.38
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分子式C22H15F3N4O2
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纯度98%
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溶解度DMSO : ≥ 33 mg/mL; 77.76 mM
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SMILESO=C(c1c2ccc(Oc3nc(N)ncc3)cc2ccc1)Nc1cccc(C(F)(F)F)c1
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化学全称6-((2-aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Halin C, et al. Am J Pathol. 2008 Jul;173(1):265-77.
产品手册
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