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Azoramide

CAS No. 932986-18-0

Azoramide ( Azoramide )

产品货号. M19268 CAS No. 932986-18-0

Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥348 有现货
10MG ¥421 有现货
25MG ¥818 有现货
50MG ¥1280 有现货
100MG ¥2333 有现货
500MG ¥5613 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Azoramide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
  • 产品描述
    Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. Azoramide mproves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems. Azoramide also exhibited potent antidiabetic efficacy in two independent mouse models of obesity by improving insulin sensitivity and pancreatic β cell function. Azoramide can be potential drug candidate for type 2 diabetes.
  • 同义词
    Azoramide
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Endocrinology
  • 适应症
    ——

化学信息

  • CAS Number
    932986-18-0
  • 分子量
    308.82
  • 分子式
    C15H17ClN2OS
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 30 mg/mL; 97.14 mM
  • SMILES
    CCCC(=O)NCCc1csc(n1)-c1ccc(Cl)cc1
  • 化学全称
    N-[2-[2-(4-chlorophenyl)-4-thiazolyl]ethyl]-butanamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Fu S, et al. Sci Transl Med. 2015 Jun 17;7(292):292ra98. doi: 10.1126/scitranslmed.aaa9134. Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
产品手册
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