Azoramide
CAS No. 932986-18-0
Azoramide ( Azoramide )
产品货号. M19268 CAS No. 932986-18-0
Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥348 | 有现货 |
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10MG | ¥421 | 有现货 |
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25MG | ¥818 | 有现货 |
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50MG | ¥1280 | 有现货 |
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100MG | ¥2333 | 有现货 |
|
500MG | ¥5613 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Azoramide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
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产品描述Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. Azoramide mproves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems. Azoramide also exhibited potent antidiabetic efficacy in two independent mouse models of obesity by improving insulin sensitivity and pancreatic β cell function. Azoramide can be potential drug candidate for type 2 diabetes.
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同义词Azoramide
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通路Others
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靶点Other Targets
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受体Others
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研究领域Endocrinology
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适应症——
化学信息
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CAS Number932986-18-0
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分子量308.82
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分子式C15H17ClN2OS
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纯度98%
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溶解度DMSO : ≥ 30 mg/mL; 97.14 mM
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SMILESCCCC(=O)NCCc1csc(n1)-c1ccc(Cl)cc1
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化学全称N-[2-[2-(4-chlorophenyl)-4-thiazolyl]ethyl]-butanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Fu S, et al. Sci Transl Med. 2015 Jun 17;7(292):292ra98. doi: 10.1126/scitranslmed.aaa9134. Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
产品手册
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