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Azimilide
CAS No. 149908-53-2
Azimilide ( NE-10064 )
产品货号. M12084 CAS No. 149908-53-2
A class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
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| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Azimilide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively.
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产品描述A class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively; blocks the rapidly activating component of the delayed rectifier, IKr (IC50=0.4 uM), and inhibits IKs (IC50=3 uM); shows anti-arrhythmic effects.Heart Arrhythmia Phase 3 Clinical
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同义词NE-10064
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通路Cell Cycle/DNA Damage
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靶点Potassium Channel
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受体Potassium Channel
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研究领域Cardiovascular Disease
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适应症Heart Arrhythmia
化学信息
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CAS Number149908-53-2
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分子量457.95
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分子式C23H28ClN5O3
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCN1CCN(CC1)CCCCN2C(=O)CN(C2=O)N=CC3=CC=C(O3)C4=CC=C(C=C4)Cl
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化学全称2,4-Imidazolidinedione, 1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Busch AE, et al. Br J Pharmacol. 1998 Jan;123(1):23-30.
2. Fermini B, et al. J Cardiovasc Pharmacol. 1995 Aug;26(2):259-71.
3. Walker BD, et al. Cardiovasc Res. 2000 Oct;48(1):44-58.
2. Fermini B, et al. J Cardiovasc Pharmacol. 1995 Aug;26(2):259-71.
3. Walker BD, et al. Cardiovasc Res. 2000 Oct;48(1):44-58.
产品手册
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