021-51111890
购物车（）
sales@molnova.cn
Azido-PEG12-acid
CAS No. 2152679-71-3
Azido-PEG12-acid ( —— )
产品货号. M26893 CAS No. 2152679-71-3
Azido-PEG12-acid 是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥470 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Azido-PEG12-acid
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Azido-PEG12-acid 是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。
-
产品描述Azido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体flap endonuclease 1 (FEN1)
-
研究领域——
-
适应症——
化学信息
-
CAS Number2152679-71-3
-
分子量643.728
-
分子式C27H53N3O14
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESOC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Application of small-molecular inhibitor SC13 targeting to FEN1 and derivative of small-molecular inhibitor SC13 in preparing tumor treatment medicine. CN106692155A.
产品手册
关联产品
-
TH5427
TH5427 是一种先导 NUDT5 抑制剂（MG 测定 IC50 = 29 nM）。
-
cAC 253
Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's disease model.
-
(R)-Apremilast
(R)-阿普司特是阿普司特的对映体，是异吲哚啉衍生物之一。
