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Avoralstat

CAS No. 918407-35-9

Avoralstat ( BCX4161 )

产品货号. M24967 CAS No. 918407-35-9

Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥551 有现货
5MG ¥915 有现货
10MG ¥1393 有现货
25MG ¥2811 有现货
50MG ¥4277 有现货
100MG ¥6229 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Avoralstat
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
  • 产品描述
    Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
  • 同义词
    BCX4161
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    plasma kallikrein (PKK)
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    918407-35-9
  • 分子量
    513.5
  • 分子式
    C28H27N5O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:50 mg/mL (97.36 mM; Need ultrasonic)
  • SMILES
    COc(c(C=C)c1)cc(-c2ccc(C(NCC3CC3)=O)nc2C(O)=O)c1C(Nc(cc1)ccc1C(N)=N)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5.
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