Autogramin-2 ( tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate )

产品货号. M24090 CAS No. 2375541-45-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Autogramin-2
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Autogramin-2 potently inhibits?autophagy?induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
产品描述

Autogramin-2 potently inhibits?autophagy?induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
同义词

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
通路

Autophagy
靶点

Autophagy
受体

autophagy
研究领域

——
适应症

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1.Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.

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