
Atezolizumab
CAS No. 1380723-44-3
Atezolizumab ( —— )
产品货号. M22134 CAS No. 1380723-44-3
Atezolizumab 抗 PD-L1)是一种完全人源化 IgG1 单克隆抗体,可阻断 PD-L1 与 PD-1 和 B7.1 的相互作用,但不能阻断 PD-L2 与 PD-1 的相互作用。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥4398 | 有现货 |
![]() ![]() |
10MG | ¥6456 | 有现货 |
![]() ![]() |
25MG | ¥9639 | 有现货 |
![]() ![]() |
50MG | ¥13203 | 有现货 |
![]() ![]() |
100MG | ¥17658 | 有现货 |
![]() ![]() |
200MG | 获取报价 | 有现货 |
![]() ![]() |
500MG | 获取报价 | 有现货 |
![]() ![]() |
1G | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称Atezolizumab
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Atezolizumab 抗 PD-L1)是一种完全人源化 IgG1 单克隆抗体,可阻断 PD-L1 与 PD-1 和 B7.1 的相互作用,但不能阻断 PD-L2 与 PD-1 的相互作用。
-
产品描述Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.
-
体外实验Atezolizumab (0, 2.5, 5, 10, 20, and 40?μg/ml; 24 hours; HOS and 143B cells) inhibits proliferation and induces immune-independent apoptosis of osteosarcoma cells.Atezolizumab impairs the function of mitochondria to cause the imbalance between oxidants and antioxidants. Atezolizumab induces mitochondria-related apoptosis of osteosarcoma cells by activating JNK pathway. Atezolizumab (10?μg/ml; 24?hours; HOS and 143B cells) induces autophagy in osteosarcoma cells.
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Other Targets
-
研究领域——
-
适应症——
化学信息
-
CAS Number1380723-44-3
-
分子量145 kDa
-
分子式——
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Inman BA, et al. Atezolizumab: A PD-L1-Blocking Antibody for Bladder Cancer. Clin Cancer Res. 2017 Apr 15;23(8):1886-1890.
产品手册




关联产品
-
Nauclefine
Nauclefine 是一种从 Nauclea officinalis 中分离出来的吲哚类生物碱。Nauclefine 可作为一种 PDE3A 调节剂,通过 PDE3A-SLFN12 依赖的死亡途径诱导癌细胞凋亡(apoptosis)。
-
Imazalil sulfate
硫酸抑霉唑是一种含咪唑基的杀菌剂,广泛用于防治植物真菌病害。
-
Derrone
Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens.