Asunaprevir

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Asunaprevir 是一种有效的丙型肝炎病毒 (HCV) NS3 蛋白酶抑制剂。

Asunaprevir, also known as BMS-650032, is an inhibitor of the hepatitis C virus enzyme serine protease NS3. Asunaprevir is being tested in combination with pegylated interferon and ribavirin, as well as in interferon-free regimens with other direct-acting antiviral agents including daclatasvir.

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BMS-650032 | BMS650032 | Asunaprevir

JAK/STAT Signaling

STAT

HCV NS3/4A protease

Infection

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630420-16-5

748.29

C35H46ClN5O9S

>98% (HPLC)

DMSO : ≥ 42.9 mg/mL; 57.33 mM

O=C([C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)N5C[C@H](Oc1ncc(OC)c2ccc(Cl)cc12)C[C@H]5C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4

1,1-dimethylethyl ((1S)-1-{((2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yloxy)-2-({(1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-ethenylcyclopropyl}carbamoyl) pyrrolidin-1-yl)carbonyl}-2,2-dimethylpropyl)carbamate

(-20℃)

With Ice Pack

≥ 2 years