Arbutamine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Arbutamine 是一种短效、强效和非选择性 β- 肾上腺素受体激动剂。Arbutamine 刺激心脏 β1-、气管 β2- 和脂肪细胞 β3- 肾上腺素受体。Arbutamine 提供心脏应激，增加心率、心脏收缩力和收缩压。Arbutamine 可用于心脏应激剂研究。

Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent .

Arbutamine (0.1-100 nM) increases heart contractile force and pD2 value of 8.45. Arbutamine has the affinity constants (KA) value of 7.32 for cardiac β1-adrenergic receptors.

Arbutamine (i.v.; 5, 10, 50, 100, and 250 ng/kg/min) increases mean heart rate, peak positive left ventricular pressure and its first time-derivative, and normal-zone myocardial thickening in 8 open-chest dogs (mean weight, 26.91 kg).

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GPCR/G Protein

Adrenergic Receptor

Adrenergic Receptor

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128470-16-6

317.38

C18H23NO4

>98% (HPLC)

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O[C@@H](CNCCCCc1ccc(O)cc1)c1ccc(O)c(O)c1

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(-20℃)

With Ice Pack

≥ 2 years