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Aniline
CAS No. 62-53-3
Aniline ( Phenylamine | Aminobenzen )
产品货号. M19715 CAS No. 62-53-3
苯胺通过铁超载和血红素加氧酶 1 上调诱导氧化应激而对脾脏有毒。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Aniline
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述苯胺通过铁超载和血红素加氧酶 1 上调诱导氧化应激而对脾脏有毒。
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产品描述Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation. Toxicity of this agent on the spleen is characterized by hyperplasia fibrosis and vascular congestion in rats. Studies suggest that this compound causes significant increase in both p-IKKα and p-IKKβ which in-turn increases NF-κB and AP-1 binding activity. In other experiments Aniline displays a capacity to induce methemoglobinemia glutathione depletion membrane cytoskeletal changes loss of circulating blood cells and adversely affects blood stability.
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体外实验——
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体内实验——
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同义词Phenylamine | Aminobenzen
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通路Proteasome/Ubiquitin
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靶点Endogenous Metabolite
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受体Human Endogenous Metabolite
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研究领域——
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适应症——
化学信息
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CAS Number62-53-3
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分子量93.13
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分子式C6H7N
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESNc1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Bomhard E M Herbold B A . Genotoxic Activities of Aniline and its Metabolites and Their Relationship to the Carcinogenicity of Aniline in the Spleen of Rats[J]. Critical Reviews in Toxicology 2005 35(10):783-835.
产品手册
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