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Aniline

CAS No. 62-53-3

Aniline ( Phenylamine;Aminobenzen )

产品货号. M19715 CAS No. 62-53-3

Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Aniline
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation.
  • 产品描述
    Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation. Toxicity of this agent on the spleen is characterized by hyperplasia fibrosis and vascular congestion in rats. Studies suggest that this compound causes significant increase in both p-IKKα and p-IKKβ which in-turn increases NF-κB and AP-1 binding activity. In other experiments Aniline displays a capacity to induce methemoglobinemia glutathione depletion membrane cytoskeletal changes loss of circulating blood cells and adversely affects blood stability.
  • 同义词
    Phenylamine;Aminobenzen
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    Endogenous Metabolite
  • 受体
    Human Endogenous Metabolite
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    62-53-3
  • 分子量
    93.13
  • 分子式
    C6H7N
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    Nc1ccccc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Bomhard E M Herbold B A . Genotoxic Activities of Aniline and its Metabolites and Their Relationship to the Carcinogenicity of Aniline in the Spleen of Rats[J]. Critical Reviews in Toxicology 2005 35(10):783-835.
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