
Amitivir
CAS No. 111393-84-1
Amitivir ( LY-217896 | LY 217896 | LY217896 )
产品货号. M27847 CAS No. 111393-84-1
阿米替韦是一种肌苷单磷酸脱氢酶抑制剂。阿米替韦抑制分裂的 MDCK 细胞的复制。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2446 | 有现货 |
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10MG | ¥3621 | 有现货 |
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25MG | ¥5978 | 有现货 |
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50MG | ¥7995 | 有现货 |
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100MG | ¥11178 | 有现货 |
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500MG | ¥22599 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Amitivir
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述阿米替韦是一种肌苷单磷酸脱氢酶抑制剂。阿米替韦抑制分裂的 MDCK 细胞的复制。
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产品描述Amitivir is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffective in modifying the virologic or clinical course of experimental influenza A (H1N1) virus infection.
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体外实验The mean 50% inhibitory concentration of Amitivir inhibits six strains of type A influenza (A/Russia, A/Brazil/11/78, A/Ann Arbor/1/57, A/Port Chalmers/1/73, A/Hong Kong/8/68 and A/X-15) ranged from 0.37 to 1.19 μg/ml. The mean 50% inhibitory concentration of Amitivir inhibits four strains of influenza B virus (B/Maryland/11/59, B/GreatLakes/1739/54, B/Singapore/3/64, B/Lee/40) ranged from 0.75 to 1.54 μg/ml.
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体内实验Amitivir (LY 217896) (9 mg/m2 of body surface area per day) administered in the diet, in the drinking water, by oral gavage, by intraperitoneal injection, or by aerosolization was well tolerated and protected CD-1 mice infected with a lethal dose of influenza A or B virus.
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同义词LY-217896 | LY 217896 | LY217896
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通路Others
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靶点Other Targets
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受体lipase
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研究领域——
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适应症——
化学信息
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CAS Number111393-84-1
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分子量126.14
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分子式C3H2N4S
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纯度>98% (HPLC)
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溶解度——
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SMILESN#CNC1=NN=CS1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Muccioli GG, et al. CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. Chembiochem. 2008 Nov 3;9(16):2704-10.
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