Amcasertib ( BBI-503 )

产品货号. M10454 CAS No. 1129403-56-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Amcasertib
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.
产品描述

A small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases; targets and inhibits one or more pathways involved in cancer stem cell survival, shows potential antineoplastic activity.Liver Cancer Phase 2 Clinical
同义词

BBI-503
通路

Others
靶点

Other Targets
受体

Others
研究领域

Cancer
适应症

Liver Cancer

CAS Number

1129403-56-0
分子量

539.69
分子式

C31H33N5O2S
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 30 mg/mL
SMILES

O=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC
化学全称

1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[[1,2-dihydro-2-oxo-5-(2-phenyl-4-thiazolyl)-3H-indol-3-ylidene]methyl]-2,4-dimethyl-

1. Marcucci F, et al. Front Oncol. 2016 May 10;6:115.
2. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8.

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