Alpha-Hederin ( alpha-Hederin )

产品货号. M18339 CAS No. 27013-91-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Alpha-Hederin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

α-常春藤素是一种水溶性五环三萜皂苷，存在于黑种草种子中，具有溶血和细胞凋亡特性。
产品描述

alpha-Hederin is Derived from beta-amyrin; other hederigenin based saponins are available. It induces apoptosis in hepatocellular carcinoma cells.(In Vitro):alpha-Hederin (α-Hederin) is cytotoxic and inhibits proliferation in both cel lines at rather low concentrations. alpha-Hederin (α-Hederin)reduces the mitotic activity in treated cells.(In Vivo):alpha-Hederin (α-Hederin) has preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses.
体外实验

alpha-Hederin (α-Hederin) is cytotoxic and inhibits proliferation in both cel lines at rather low concentrations. alpha-Hederin (α-Hederin)reduces the mitotic activity in treated cells.
体内实验

alpha-Hederin (α-Hederin) has preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses.
同义词

alpha-Hederin
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

27013-91-8
分子量

750.97
分子式

C41H66O12
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 100 mg/mL 133.16 mM; H2O : < 0.1 mg/mL
SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]1[C@H]([C@H](CO[C@H]1O[C@H]1CC[C@]2([C@H]([C@]1(C)CO)CC[C@@]1([C@@H]2CC=C2[C@]1(CC[C@@]1([C@H]2CC(CC1)(C)C)C(=O)O)C)C)C)O)O)O)O)O
化学全称

(4alpha)-3beta-((2-O-(6-Deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl)oxy)-23-hydroxyolean-12-en-28-oic acid