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Alofanib

CAS No. 1612888-66-0

Alofanib ( —— )

产品货号. M19902 CAS No. 1612888-66-0

Alofanib is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥583 有现货
10MG ¥786 有现货
25MG ¥1725 有现货
50MG ¥2576 有现货
100MG ¥3993 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Alofanib
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Alofanib is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM).
  • 产品描述
    Alofanib is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM).
  • 同义词
    ——
  • 通路
    Angiogenesis
  • 靶点
    ALK
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1612888-66-0
  • 分子量
    ——
  • 分子式
    C19H15N3O6S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 50 mg/mL;Water: Insoluble
  • SMILES
    Cc1cc(c(NS(=O)(=O)c2cccc(c2)C(O)=O)cc1-c1cccnc1)[N+]([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    ——
  • 稳定性
    ≥ 2 years

参考文献

1.Tyulyandina A et al. Alofanib an allosteric FGFR2 inhibitor has potent effects on ovarian cancer growth in preclinical studies. Invest New Drugs. 2017 Apr;35(2):127-133.
产品手册
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