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Alfacalcidol

CAS No. 41294-56-8

Alfacalcidol ( 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3 )

产品货号. M17506 CAS No. 41294-56-8

Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥356 有现货
5MG ¥567 有现货
10MG ¥794 有现货
25MG ¥1758 有现货
50MG ¥2795 有现货
100MG ¥4431 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Alfacalcidol
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.
  • 产品描述
    Alfacalcidol is an active metabolite of Vitamin D, which performs important functions in regulation of the calcium balance and the bone metabolism. Alfacalcidol is Vitamin D-hormone analog which is activated by the enzyme 25-hydroxylase in the liver for systemic and in osteoblasts for local D-hormone actions. It possesses a unique pattern of pleiotropic effects on, e.g. gut, bone, pararthyroids, muscle and brain. Alfacalcidol is superior to plain vitamin D (cholecalciferol) because the final kidney activation of the latter is regulated by a negative feedback mechanism.
  • 同义词
    1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Metabolic Disease
  • 适应症
    ——

化学信息

  • CAS Number
    41294-56-8
  • 分子量
    400.64
  • 分子式
    C27H44O2
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 50 mg/mL. 124.80 mM; H2O : < 0.1 mg/mL
  • SMILES
    [H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CCC\C2=C\C=C1/C[C@@H](O)C[C@H](O)C1=C
  • 化学全称
    (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Munisamy S, Daud KM, Mokhtar SS, Rasool AH.Microcirculation. 2016 Jan;23(1):53-61.
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