
Alfacalcidol
CAS No. 41294-56-8
Alfacalcidol ( 1-hydroxycholecalciferol | 1.alpha.-Hydroxyvitamin D3 )
产品货号. M17506 CAS No. 41294-56-8
阿法骨化醇(1-羟基胆钙化醇;Alpha D3;1.α.-羟基维生素 D3)是一种非选择性 VDR 激活剂化合物。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥356 | 有现货 |
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5MG | ¥567 | 有现货 |
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10MG | ¥794 | 有现货 |
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25MG | ¥1758 | 有现货 |
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50MG | ¥2795 | 有现货 |
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100MG | ¥4431 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Alfacalcidol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述阿法骨化醇(1-羟基胆钙化醇;Alpha D3;1.α.-羟基维生素 D3)是一种非选择性 VDR 激活剂化合物。
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产品描述Alfacalcidol is an active metabolite of Vitamin D, which performs important functions in regulation of the calcium balance and the bone metabolism. Alfacalcidol is Vitamin D-hormone analog which is activated by the enzyme 25-hydroxylase in the liver for systemic and in osteoblasts for local D-hormone actions. It possesses a unique pattern of pleiotropic effects on, e.g. gut, bone, pararthyroids, muscle and brain. Alfacalcidol is superior to plain vitamin D (cholecalciferol) because the final kidney activation of the latter is regulated by a negative feedback mechanism.
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体外实验——
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体内实验Animal Model:Female Wistar-Imamichi rats (8 months old), ovariectomized Dosage:0.025 mg/kg, 0.05 mg/kg, 0.1 mg/kg Administration:Oral administration; five times a week; for 3 months Result:Exerted bone-protective effects independently of its Ca-related effects
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同义词1-hydroxycholecalciferol | 1.alpha.-Hydroxyvitamin D3
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通路Others
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靶点Other Targets
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受体Others
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研究领域Metabolic Disease
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适应症——
化学信息
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CAS Number41294-56-8
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分子量400.64
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分子式C27H44O2
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 50 mg/mL. 124.80 mM; H2O : < 0.1 mg/mL
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SMILES[H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CCC\C2=C\C=C1/C[C@@H](O)C[C@H](O)C1=C
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化学全称(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Munisamy S, Daud KM, Mokhtar SS, Rasool AH.Microcirculation. 2016 Jan;23(1):53-61.
产品手册




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