Agipnon

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Bemegride 是一种中枢神经系统兴奋剂和巴比妥中毒的解毒剂。

Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.(In Vitro):Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression.

Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression.

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Bemegride | Antibarbi | Agipnon | Ahypnon | Eukraton | Malysol | Mikedimide | Zentraleptin

Membrane Transporter/Ion Channel

GAT

GABAR

Neurological Disease

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64-65-3

155.19

C8H13NO2

>98% (HPLC)

Ethanol: 31 mg/mL (199.75 mM); DMSO: 31 mg/mL (199.75 mM)

O=C(CC(C)(CC)C1)NC1=O

2,6-Piperidinedione, 4-ethyl-4-methyl-

(-20℃)

With Ice Pack

≥ 2 years