Adjudin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.

Adjudin, also known as AF-2364, is a drug which is under development as a potential non-hormonal male contraceptive drug, which acts by blocking the production of sperm in the testes, but without affecting testosterone production. It is an analogue of the chemotherapy drug lonidamine, an indazole-carboxylic acid, and further studies continue to be conducted into this family of drugs as possible contraceptives. A study in 2013 indicated that Adjudin, similar to its analogue lonidamine, has properties that inhibit cancer growth by targeting mitochondria and blocking energy metabolism in certain kinds of tumor cells in mice, indicating that it has potential as a drug for cancer therapy.

AF-2364; AF 2364; AF2364; Adjudin

Others

Other Targets

Others

Others-Field

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252025-52-8

335.19

C15H12Cl2N4O

97%

DMSO : ≥ 34 mg/mL; 101.44 mM

Clc1c(Cn2nc(c3c2cccc3)C(=O)NN)ccc(Cl)c1

1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide

(-20℃)

With Ice Pack

≥ 2 years