
Aconine
CAS No. 509-20-6
Aconine ( Jesaconine )
产品货号. M18683 CAS No. 509-20-6
乌头碱具有胃麻醉作用。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥915 | 有现货 |
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10MG | ¥1531 | 有现货 |
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25MG | ¥2584 | 有现货 |
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50MG | ¥3848 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Aconine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述乌头碱具有胃麻醉作用。
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产品描述Aconine is the febrifuge. Aconine possesses gastric anaesthetic props.
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体外实验Treatment with Aconine significantly inhibits the RANKL-induced transcriptional activity of NF-κB in a dose-dependent manner. Aconine inhibits RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing the activation of NF-κB and NFATc1 and the expression of the cell-cell fusion molecule DC-STAMP. Aconine (0.125, 0.25 μM) does not affect the viability of RAW264.7 cells, but dose-dependently inhibits RANKL-induced osteoclast formation and bone resorptive activity. Aconine dose-dependently inhibits the RANKL-induced activation of NF-κB and NFATc1 in RAW264.7 cells, and subsequently reduces the expression of osteoclast-specific genes (c-Src, β3-Integrin, cathepsin K and MMP-9) and the expression of dendritic cell-specific transmembrane protein (DC-STAMP), which plays an important role in cell-cell fusion.
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体内实验——
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同义词Jesaconine
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通路Others
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靶点Other Targets
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number509-20-6
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分子量499.6
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分子式C25H41NO9
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 125 mg/mL; 250.21 mM
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SMILESCCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6O)(C(C5O)OC)O)O)OC)OC)O)COC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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