
Acetylcorynoline
CAS No. 18797-80-3
Acetylcorynoline ( —— )
产品货号. M18162 CAS No. 18797-80-3
通过阻断树突状细胞的成熟和功能,乙酰皮质啉可能是一种有效的免疫抑制剂。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2161 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Acetylcorynoline
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述通过阻断树突状细胞的成熟和功能,乙酰皮质啉可能是一种有效的免疫抑制剂。
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产品描述Acetylcorynoline has antifungal、anti-inflammatory activity. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.
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体外实验Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs).Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Antifungal
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研究领域Others-Field
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适应症——
化学信息
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CAS Number18797-80-3
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分子量409.43
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分子式C23H23NO6
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 25 mg/mL (61.06 mM)
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SMILESCC(=O)OC1CC2=CC3=C(C=C2C4C1(C5=C(CN4C)C6=C(C=C5)OCO6)C)OCO3
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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