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Acetylcorynoline

CAS No. 18797-80-3

Acetylcorynoline ( —— )

产品货号. M18162 CAS No. 18797-80-3

通过阻断树突状细胞的成熟和功能,乙酰皮质啉可能是一种有效的免疫抑制剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2161 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Acetylcorynoline
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    通过阻断树突状细胞的成熟和功能,乙酰皮质啉可能是一种有效的免疫抑制剂。
  • 产品描述
    Acetylcorynoline has antifungal、anti-inflammatory activity. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.
  • 体外实验
    Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs).Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Antifungal
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    18797-80-3
  • 分子量
    409.43
  • 分子式
    C23H23NO6
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 25 mg/mL (61.06 mM)
  • SMILES
    CC(=O)OC1CC2=CC3=C(C=C2C4C1(C5=C(CN4C)C6=C(C=C5)OCO6)C)OCO3
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

产品手册
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