Ac-Arg-OH

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Na-乙酰基-L-精氨酸，也称为N-ac-L-arg-OH或N-α-乙酰精氨酸，属于称为n-酰基-1-α-氨基酸的有机化合物类别。

N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-arginine serum levels (and other guanidino compounds) were elevated of all the hyperargininemic patients are higher than the normal range. N-a-Acetyl-L-arginine is a very strong basic compound (based on its pKa). Untreated hyperargininemic patients have the highest guanidino compound levels in cerebrospinal fluid. N-a-Acetyl-L-arginine is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population. Outside of the human body N-a-Acetyl-L-arginine has been detected but not quantified in apples and loquats. This could make N-a-acetyl-L-arginine a potential biomarker for the consumption of these foods. N-a-Acetyl-L-arginine with regard to humans has been found to be associated with several diseases such as uremia and colorectal cancer; N-a-acetyl-L-arginine has also been linked to the inborn metabolic disorder hyperargininemia. During a low-arginine diet together with sodium benzoate therapy there was a marked decrease in plasma N-alpha-acetylarginine. N-a-Acetyl-L-arginine increases in urine hyperargininemic patients.

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Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

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155-84-0

216.24

C8H16N4O3

>98% (HPLC)

DMSO:43 mg/mL (198.85 mM)

CC(N[C@@H](CCCNC(N)=N)C(O)=O)=O

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(-20℃)

With Ice Pack

≥ 2 years