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Ac-Arg-OH

CAS No. 155-84-0

Ac-Arg-OH ( —— )

产品货号. M21398 CAS No. 155-84-0

N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG ¥332 有现货
200MG ¥470 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ac-Arg-OH
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids.
  • 产品描述
    N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-arginine serum levels (and other guanidino compounds) were elevated of all the hyperargininemic patients are higher than the normal range. N-a-Acetyl-L-arginine is a very strong basic compound (based on its pKa). Untreated hyperargininemic patients have the highest guanidino compound levels in cerebrospinal fluid. N-a-Acetyl-L-arginine is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population. Outside of the human body N-a-Acetyl-L-arginine has been detected but not quantified in apples and loquats. This could make N-a-acetyl-L-arginine a potential biomarker for the consumption of these foods. N-a-Acetyl-L-arginine with regard to humans has been found to be associated with several diseases such as uremia and colorectal cancer; N-a-acetyl-L-arginine has also been linked to the inborn metabolic disorder hyperargininemia. During a low-arginine diet together with sodium benzoate therapy there was a marked decrease in plasma N-alpha-acetylarginine. N-a-Acetyl-L-arginine increases in urine hyperargininemic patients.
  • 同义词
    ——
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    Endogenous Metabolite
  • 受体
    Human Endogenous Metabolite
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    155-84-0
  • 分子量
    216.24
  • 分子式
    C8H16N4O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:43 mg/mL (198.85 mM)
  • SMILES
    CC(N[C@@H](CCCNC(N)=N)C(O)=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.De Deyn PP et al. Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations. Nephron. 1995;69(4):411-7.
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