AZD3463 ( AZD3463; AZD 3463; AZD-3463 )

产品货号. M11460 CAS No. 1356962-20-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AZD3463
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
产品描述

AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
同义词

AZD3463; AZD 3463; AZD-3463
通路

Angiogenesis
靶点

ALK
受体

ALK
研究领域

Cancer
适应症

——

CAS Number

1356962-20-3
分子量

448.95
分子式

C24H25ClN6O
纯度

>98%(HPLC)
溶解度

DMSO: 24 mg/mL (53.45 mM)
SMILES

ClC1=CN=C(NC2=CC=C(N3CCC(N)CC3)C=C2OC)N=C1C4=CNC5=C4C=CC=C5
化学全称

N-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine.

1.104th AACR meeting, 2013, Abst 919.

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