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AZ13705339

CAS No. 2016806-57-6

AZ13705339 ( AZ-13705339; AZ 13705339 )

产品货号. M27853 CAS No. 2016806-57-6

AZ13705339 is a potent and selective PAK1 inhibitor with IC50 of 0.33 nM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥316 有现货
5MG ¥518 有现货
10MG ¥794 有现货
25MG ¥1798 有现货
50MG ¥2876 有现货
100MG ¥4633 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    AZ13705339
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    AZ13705339 is a potent and selective PAK1 inhibitor with IC50 of 0.33 nM.
  • 产品描述
    AZ13705339 is a potent and selective PAK1 inhibitor with IC50 of 0.33 nM.(In Vitro):AZ13705339 (300 nM) prevents Siglec-8 binding-induced eosinophil death. In Namalwa cells, AZ13705339 (1 μM) inhibits αIgM-controlled but not PMA-induced adhesion.(In Vivo):In rats, AZ13705339 (100 mg/kg, p.o.) exhibits moderate clearance and Cmax of 7.7 μM.
  • 同义词
    AZ-13705339; AZ 13705339
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2016806-57-6
  • 分子量
    629.8
  • 分子式
    C33H36FN7O3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CCS(=O)(=O)c1cc(Nc2ncc(F)c(n2)N(Cc2ccccc2C#N)c2cc(CO)ccc2C)ccc1N1CCN(C)CC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Andrew F Ducruet , et al. GM1485, a Nonimmunosuppressive Immunophilin Ligand, Promotes Neurofunctional Improvement and Neural Regeneration Following Stroke. J Neurosci Res. 2012 Jul;90(7):1413-23.
产品手册
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