021-51111890
购物车（）
sales@molnova.cn
AS057278
CAS No. 402-61-9
AS057278 ( 3-Methylpyrazole-5-carboxylic acid )
产品货号. M20843 CAS No. 402-61-9
AS057278 是一种 D-氨基酸氧化酶 (DAAO) 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥356 | 有现货 |
|
| 5MG | ￥583 | 有现货 |
|
| 10MG | ￥915 | 有现货 |
|
| 25MG | ￥1523 | 有现货 |
|
| 50MG | ￥2292 | 有现货 |
|
| 100MG | ￥3418 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称AS057278
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述AS057278 是一种 D-氨基酸氧化酶 (DAAO) 抑制剂。
-
产品描述AS057278 is an D-amino acid oxidase (DAAO) inhibitor.
-
体外实验——
-
体内实验AS057278 (PO; 20 mg/kg b.i.d for 28 days; 80 mg/kg single dosage) normalizes?phencyclidine?(PCP)-induced?prepulse inhibition.AS057278 (10 mg/kg; PO and IV; single dosage) exhibits good pharmacokinetic effects.Pharmacokinetic Parameters of AS057278 in male Sprague-Dawley rats. Animal Model:Males C57BL/6J miceDosage:80 mg/kg, 20 mg/kg Administration:PO; 20 mg/kg b.i.d for 28 days; 80 mg/kg single dosage Result:Normalized?phencyclidine?(PCP)-induced?prepulse inhibition?after acute (80?mg/kg) and chronic (20?mg/kg b.i.d.)?oral administration?in mice.Animal Model:Male Sprague-Dawley ratsDosage:10 mg/kg Administration:PO and IV; single dosage (Pharmacokinetics Analysis)Result:Exhibited good pharmacokinetic effect.
-
同义词3-Methylpyrazole-5-carboxylic acid
-
通路Others
-
靶点Other Targets
-
受体D-amino acid oxidase (DAAO)
-
研究领域——
-
适应症——
化学信息
-
CAS Number402-61-9
-
分子量126.11
-
分子式C5H6N2O2
-
纯度>98% (HPLC)
-
溶解度DMSO:25mg/mL(198.24mM)
-
SMILESCc1cc(C(=O)O)n[nH]1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Adage T Anne-Cécile Trillat Quattropani A et al. In vitro and in vivo pharmacological profile of AS057278 a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties[J]. European Neuropsychopharmacology the Journal of the European College of Neuropsychopharmacology 2008 18(3):200-214.
产品手册
关联产品
-
Leucocrystal Violet
无色龙胆紫是一种小分子，分子式为 C25H31N3。
-
Inotodiol
Inotodiol is an included triterpenoid with a significant effect of anti-tumor.
-
Fmoc-Phe(4-CN)-OH
Fmoc-Phe(4-CN)-OH 是一种 N-Fmoc 保护的苯丙氨酸衍生物，也是潜在有用的合成中间体。
