AOB2796
CAS No. 916170-19-9
AOB2796 ( AC-55541; AC 55541; AC55541 )
产品货号. M17660 CAS No. 916170-19-9
AOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥689 | 有现货 |
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10MG | ¥1199 | 有现货 |
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25MG | ¥2049 | 有现货 |
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50MG | ¥3054 | 有现货 |
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100MG | ¥4520 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称AOB2796
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述AOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
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产品描述AC-55541 is a protease-activated receptor (PAR) 2 agonist. AC-55541activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. AC-55541 was well absorbed when administered intraperitoneally to rats, each reaching micromolar peak plasma concentrations. AC-55541 was stable to metabolism by liver microsomes and maintained sustained exposure in rats, with elimination half-lives of 6.1. Systemic administration of either AC-55541 or AC-264613 produced a similar degree of hyperalgesia as was observed when the compounds were administered locally. AC-55541 may be useful in probing the physiological functions of PAR2 receptors.
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同义词AC-55541; AC 55541; AC55541
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通路Others
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靶点Other Targets
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受体Protease-Activated Receptor 2
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研究领域Others-Field
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适应症——
化学信息
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CAS Number916170-19-9
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分子量518.36
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分子式C25H20BrN5O3
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纯度98%
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溶解度DMSO : ≥ 51 mg/mL;;98.39 mM
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SMILESC/C(=N\NC(=O)C(c1n[nH]c(=O)c2ccccc12)NC(=O)c1ccccc1)/c1cc(ccc1)Br
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化学全称(E)-N-(2-(2-(1-(3-bromophenyl)ethylidene)hydrazinyl)-2-oxo-1-(4-oxo-3,4-dihydrophthalazin-1-yl)ethyl)benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Gardell LR, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808.
产品手册
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