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AN12855
CAS No. ——
AN12855 ( AN-12855;AN 12855 )
产品货号. M17107 CAS No. ——
AN12855 (AN-12855) is potent, cofactor-independent M. tuberculosis InhA inhibitor, binds to and inhibits InhA with IC50 of 0.03 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称AN12855
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述AN12855 (AN-12855) is potent, cofactor-independent M. tuberculosis InhA inhibitor, binds to and inhibits InhA with IC50 of 0.03 uM.
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产品描述AN12855 (AN-12855) is potent, cofactor-independent M. tuberculosis InhA inhibitor, binds to and inhibits InhA with IC50 of 0.03 uM, shows potent activity against whole-cell M. tuberculosis H37Rv with IC90 of 0.09 uM; AN12855 demonstrates potent activity against drug-susceptible and drug-resistant strains of M. tuberculosis, exhibits comparable efficacy to the frontline antitubercular drug isoniazid (INH) in both acute and chronic models of TB infection with a lower potential for resistance development and shows in vitro activity against conventional KatG-mediated INH-resistant M. tuberculosis.
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同义词AN-12855;AN 12855
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量441.19
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分子式C17H15BF3N3O5S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称(E)-2-((2-(ethylsulfonyl)-1-hydroxy-1,2-dihydrobenzo[d][1,2,3]diazaborinin-7-yl)oxy)-5-(trifluoromethyl)benzaldehyde oxime
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Xia Y, et al. Life Sci Alliance. 2018 Jun 1;1(3):e201800025.
2. Robertson GT, et al. Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02071-18.
2. Robertson GT, et al. Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02071-18.
产品手册
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