AMI-193 ( Spiramide; Espiramida )

产品货号. M27476 CAS No. 510-74-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

AMI-193
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AMI-193 is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor.
产品描述

AMI-193 is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor. AMI-193 shows antipsychotic activity.(In Vivo):In adult male squirrel monkeys, AMI-193 (0.003 and 0.01 mg/kg; i.m.) decreases the response rate under a fixed-interval (FI) schedule of stimulus termination in a dose-dependent manner and under a second-order schedule of i.v. self-administration of cocaine (0.1 mg/infusion). AMI-193 (0.003 and 0.01 mg/kg; i.m.) attenuates the discriminative-stimulus effects of cocaine.
同义词

Spiramide; Espiramida
通路

GPCR/G Protein
靶点

Dopamine Receptor
受体

——
研究领域

——
适应症

——

1.Decktor DL, et al. Lidamidine inhibits intrinsic contractile patterns of the rat proximal colon. Eur J Pharmacol. 1987 Nov 10;143(2):213-9.

计算器

产品手册

关联产品

Levosulpiride

Levosulpiride is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic drug of the benzamide class.
Raclopride

Raclopride is a selective antagonist of dopamine D2/D3 receptor.
Gemcitabine monophos...

Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.