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AMAROGENTIN
CAS No. 21018-84-8
AMAROGENTIN ( —— )
产品货号. M20171 CAS No. 21018-84-8
Amarogentin主要从獐牙菜和龙胆根中提取。它通过调节细胞周期和细胞凋亡在肝癌发生过程中发挥预防/治疗作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥810 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AMAROGENTIN
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Amarogentin主要从獐牙菜和龙胆根中提取。它通过调节细胞周期和细胞凋亡在肝癌发生过程中发挥预防/治疗作用。
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产品描述Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis.
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体外实验——
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体内实验Animal Model:Carbon tetrachloride (HY-Y0298)-induced liver fibrosis mice modelDosage:100 mg/kg Administration:p.o.Result:Decreased hepatic α-SMA and TGF-β1 expression.Inhibited phosphorylation of JNK, ERK, and p38.
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点AMPK
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受体AMPK
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研究领域——
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适应症——
化学信息
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CAS Number21018-84-8
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分子量586.54
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分子式C29H30O13
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纯度>98% (HPLC)
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溶解度DMSO:2 mg/mL?(3.4 mM)
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SMILES[H][C@@]12CCOC(=O)C1=CO[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1OC(=O)c1c(O)cc(O)cc1-c1cccc(O)c1)[C@@H]2C=C
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化学全称(11'-Biphenyl)-2-carboxylic acid 33'5-trihydroxy- 2-ester with 5-ethenyl-6-(beta-D-glucopyranosyloxy)-44a56-tetrahydro-1H3H-pyrano(34-c)pyran-1-one (4aS-(4aalpha5beta6alpha))-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shantanu S Khushboo B Durai S et al. The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin a Secoiridoid Glycoside from Swertia chirayita[J]. PLoS ONE 2014 9(3):e90637-.
