ALPHA-PINENE

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

ALPHA-PINENE 是一种双环单萜，存在于松树和其他植物中，包括具有多种生物活性的大麻。它减少了 7 种革兰氏阳性菌、7 种革兰氏阴性菌和 8 种酵母菌株的生长，MIC 值分别为 0.75-1.29、1.05-1.59 和 0.7-1.17%。它对 C. molestus 幼虫具有杀虫活性，LC50 值范围为 47 至 49 mg/L。它 (100 μg/ml) 可诱导细胞凋亡，增加阴离子超氧化物的产生和 DNA 片段化，并激活 B16/ 中的 Caspase-3 F10 黑色素瘤细胞 。

α-Pinene is a bicyclic monoterpene found in pine trees and other plants, including Cannabis with diverse biological activities. It reduces the growth of a panel of seven Gram-positive bacteria, seven Gram-negative bacteria, and eight yeast strains with MIC values of 0.75-1.29, 1.05-1.59, and 0.7-1.17%, respectively. It has insecticidal activity against C. molestus larvae with LC50 values ranging from 47 to 49 mg/L.3 α-Pinene (100 μg/ml) induces apoptosis, increases anion superoxide production and DNA fragmentation, and activates caspase-3 in B16/F10 melanoma cells [4]. In a B16/F10 mouse xenograft model, α-pinene (100 ml of a 10 mg/ml solution) reduces the number of metastatic lung nodules by approximately 7-fold. α-Pinene (8.6 mg/L, aerosol) also increases the time spent in the open arms of the elevated plus maze by approximately 2-fold in mice, indicating anxiolytic-like activity.

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Immunology/Inflammation

PGE synthase

Antifungal

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2437-95-8

136.23

C10H16

>98% (HPLC)

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CC2(C)C1CC=C(C)C2C1

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(-20℃)

With Ice Pack

≥ 2 years