AKBA ( AKBA | 3-O-acetyl-11-keto-β-Boswellic acid )

产品货号. M18980 CAS No. 67416-61-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

AKBA
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

3-O-Acetyl-11-keto-beta-boswellic Acid 可抑制 5-脂氧合酶产物的形成，IC(5) 为 1.5 m muM。
产品描述

AKBA is an antiangiogenic and neuroprotective agent, reducing the impact of proliferative retinopathies, protecting neurons against ischemic injury involving the Nrf2/HO-1 pathway. It selectively inhibits 5-lipoxygenase (IC50 = 1.5 μM) in an enzyme-directed, nonredox, and noncompetitive manner.2 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.
体外实验

——
体内实验

——
同义词

AKBA | 3-O-acetyl-11-keto-β-Boswellic acid
通路

Others
靶点

Other Targets
受体

Others
研究领域

Cancer
适应症

——

CAS Number

67416-61-9
分子量

512.73
分子式

C32H48O5
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 5.2 mg/mL; 10.14 mM
SMILES

CC1CCC2(CCC3(C(=CC(=O)C4C3(CCC5C4(CCC(C5(C)C(=O)O)OC(=O)C)C)C)C2C1C)C)C
化学全称

(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid

计算器

产品手册

关联产品

Glycyrin

Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
Mauritianin

Mauritianin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica and is a topoisomerase I inhibitor.Mauritianin has cytoprotective activity.
VH032-cyclopropane-F

VH032-环丙烷-F 是基于 VH032 的 VHL 配体。 VH032-环丙烷-F可以通过接头连接至蛋白质配体以形成PROTAC。 PROTAC 1 是 SMARCA2 和 SMARCA4 的部分降解剂。