AKBA ( AKBA; 3-O-acetyl-11-keto-β-Boswellic acid )

产品货号. M18980 CAS No. 67416-61-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AKBA
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 1.5 m muM.
产品描述

AKBA is an antiangiogenic and neuroprotective agent, reducing the impact of proliferative retinopathies, protecting neurons against ischemic injury involving the Nrf2/HO-1 pathway. It selectively inhibits 5-lipoxygenase (IC50 = 1.5 μM) in an enzyme-directed, nonredox, and noncompetitive manner.2 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.
同义词

AKBA; 3-O-acetyl-11-keto-β-Boswellic acid
通路

Others
靶点

Other Targets
受体

Others
研究领域

Cancer
适应症

——

CAS Number

67416-61-9
分子量

512.73
分子式

C32H48O5
纯度

98%
溶解度

DMSO : ≥ 5.2 mg/mL; 10.14 mM
SMILES

CC1CCC2(CCC3(C(=CC(=O)C4C3(CCC5C4(CCC(C5(C)C(=O)O)OC(=O)C)C)C)C2C1C)C)C
化学全称

(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid

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