AI-10-47
CAS No. 1256094-31-1
AI-10-47 ( 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47 )
产品货号. M23426 CAS No. 1256094-31-1
AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1320 | 有现货 |
|
10MG | ¥2341 | 有现货 |
|
25MG | ¥4358 | 有现货 |
|
50MG | ¥6294 | 有现货 |
|
100MG | ¥8829 | 有现货 |
|
500MG | ¥17577 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称AI-10-47
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).
-
产品描述AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).
-
同义词1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47
-
通路Others
-
靶点Other Targets
-
受体CBFβ-RUNX binding
-
研究领域——
-
适应症——
化学信息
-
CAS Number1256094-31-1
-
分子量279.2
-
分子式C13H8F3N3O
-
纯度>98% (HPLC)
-
溶解度DMSO:100 mg/mL (358.14 mM; Need ultrasonic)
-
SMILESFC(F)(F)OC1=CC=C2N=C(C3=NC=CC=C3)NC2=C1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Anuradha Illendula, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016 Jun;8:117-131.
产品手册
关联产品
-
F1324
F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.
-
KL201
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.